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GET USE FOR UR EXAMS hope it might help you DIURETICS Type of diuretics Drug P rimar y Site of action Other sites effect on renal hemodynamics Excreted ions pH uses Adverse effects Carbonic anhydrase inhibition [ abolish NaHCO3 reabsorption in proximal tubule] Acetazolamide (DIAMOX), Dichlorphenamide (DARAMIDE), Methazolamide (GLAUCTABS). Proximal tubular epithelial cells Collecting ducts Increase delivery of solutes to the macula densa , increase afferent arteriolar resistance and reduces renal blood flow and GFR Increasing HCO3 –  & phosphate excretion Increase in urinary Ph –> metabolic acidosis Edema , treat epilepsy, relief in patients with high-altitude illness or mountain sickness , useful in pts with familial periodic paralysis, treatment of dural ectasia in individulas with marfansyndrome, of sleep apnea, and of idiopathic intracranial hypertension , correct metabolic alkalosis. Large doses exhibit

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                                                        PNEUMONIA P neumonia is an infectious disease affecting lung parenchyma. It is a respiratory disease caused by inflammation of the lung parenchyma caused by viruses, bacteria or irritants introduced into the lungs through hematogenous spread or by inhalation. It's one of the most leading cause of death in children under 5 years of age.  It's classified into community acquired , Hospital acquired , Ventilator associated pneumonia. Epidemiology : Pneumonia globally very serious problem killing 1000s of people world wide. Though well developed countries with new technologies it does not reduce it's affect on people because of life styles of human beings and MDR (multidrug resistance) pathogens , high virulence capacity of the microbes. Etiology: Common pathogens that cause Pneumonia are the following Clinical manifestations :   Cough is the most common complaint, it may be productive or nonproductive. Tachyp