DRUG OF CHOICE


                                           Drugs Of Choice List in infections

(1)Penicillin G
Streptococcus pneumoniae, S.Viridans,Hemolytic Streptococci group A,B,C,G,Staphylococcus (Non-Penicillinase producing)
Neisseria Meningitidis,Clostridium(ABC)Bacillus Cereus,Actinomyces.Treponema Pallidum, T.Pertene
(2)Ampicillin
Listeria,Enterococcus faecalis.
(3)Vancomycin
MRSA,Coagulase negative staphylococcus,Enterococcus faecium.
(4)Erythromycin
Corynebacterium
(5)Doxycycline
Bacillus anthracis,
Borelia burgdorferi, B.Recurrentis.
Chalmydia & Rickettsiae.
(6) Cotrimoxazole
Nocardia
(7) Azithromycin
Hemophilus ducreyi & Mycoplasma .
(8) Ceftriaxone
Proteus,E.coli,Salmonella
(9)Carbapenems
Serratia,Enterobacter,Acinetobacter
(10)(Metronidazole
Bacteriocides
(11)Ceftazidime
Burkholderia pseudomallei

Drugs Of Choice List in pregnancy

(12)Choloroquine
Drug of choice for malaria in pregnancy
(13) Alpha-Methyldopa
DoC for hypertension in pregnancy
(14)Heparin
DOC for anticoagulation in pregnancy.
(15)Labetalol
DOC for hypertensive crisis in pregnant women.
(16)Acetaminophen
Analgesic DOC
(17)Phenobarbitone
DoC for epilepsy in pregnant women.
(18)Doxylamine & Pyridoxine
DoC for nausea in pregnancy.

 Drugs Of Choice List for various types of seizures:

(19)Valproate
Tonic seizures
Absence seizures
Grand mal (GTCS)
Clonic seizures
Atonic seizures
Myoclonic seizures
(20)Carbamazepine
Partial seizures
(21)Vigabatrin
Infantile spasm with tuberous sclerosis
(22)ACTH
Infantile spasm
(23)Lorazepam (IV)
Status epilepticus
(24)Diazepam
Febrile seizures
(25)Magnesium Sulphate
Seizure in eclampsia

Drugs Of Choice List in poisoning

(26)Physostigmine
Atropine, Belladona & Dhatura poisoning
(27)Atropine
Carbamate,Early mushroom poisoning,Organophosphate poisoning.
(28)Flumazenil
Benzodiazepine poisoning
(29)Acetylcystine
Acetaminophen poisoning
(30)Nalaxone
Opoid poisoning
(31)Deferiprone
Chronic iron poisoning
(32)Desferrioxamine
Acute iron poisoning
(33)Glucagon
Beta blockers poisoning
(34)Amyl nitrate
Cyanide poisoning

Drugs Of Choice List in bronchial asthma

(35)Salbutamol
Acute attack of bronchial ashtma in normal patient and pregnant women.
Exercise & Aspirin-induced acute attack of bronchial asthma.
(36)Ipratropium
Acute attack of bronchial asthma during labour.
Acute attack of bronchial ashtma on beta-blockers therapy.
(37)Corticosteroids
Prophylaxis of bronchial asthma ,exercise induced and aspirin-induced asthma.

Drugs Of Choice List In Antimicrobials Prophylaxis

(38)Ampicillin
Group B streptococcus infection
(39)Amoxicillin
Endocarditis and Otitis media
(40)Azithromycin
Mycobacterium avium complex (MAC) Pertussis
(41)Benzathine penicillin
Rheumatic fever
(42)Procaine Penicillin
Gonorrhea and syphilis
(43)Tetracycline
Rickettsial infection and plague.
(44)Cefazoline
Surgical Prophylaxis
(45)Doxycycline
Anthrax
(46)Trimethoprim and sulphamethoxazole
Toxoplasmosis , Pneumocystis jerveci UTI
(47)Rifampicin
Hemophilus influenza type B.
(48)Oseltamivir
Influenza Type A & B.

 Anesthetic Drugs Of Choice List

(49)Propofol
Day care
(50)Sevoflurane
Congenital heart disease,ASD,VSD,PDA
(51)Etomidate
Ischemic heart disease
(52)Ketamine
Asthma and COPD
Shock
CHF, and congenital heart disease (Right to left shunt)
(53)Thiopentone
Epilepsy
Thyrotoxicosis
(54)Methohexitone
Electroconvulsion therapy
(55)Isoflurane
Cardiac surgery
Neurosurgery
For producing deliberate hypotension

Drugs Of Choice List in Endocrinological Disorders

(56)Insulin
Type 1 DM
Diabetes Mellitus in pregnancy.
Diabetic Ketoacidosis.
Uncontrolled DM.
(57)Metformin
Type 2 DM
Diabetes mellitus in obesity
(58)Sildenafil
Erectile Dysfunction
(59)Hydrocortisone
Acute and chronic adrenal insufficiency.
(60)Nateglinide
Post prandial hyperglycemia.
(61)Methotrexate
Ectopic pregnancy
(62)Oxytocin
Post partum hemorrhage
Induction of labour
(63)Cabergoline
Acromegaly
Hyperprolactinemia.
(64)Finasteride
Andogeni
tal alopecia.
(65)Alendronate
Osteoporosis

 Drugs of choice in fungal infections

(66)Amphotericin B
Meningeal histoplasmosis
Endocarditis by candida
Sever or CNS blastomycosis
Induction i cryptococcal meningitis(For 2 weeks)
Exserohium
(67)Fluconazole
Candida albicans
Maintainance in cryptococcal meningitis
(68)itraconazole
Non meningeal histoplasmosis
Sporotrichosis
Para Coccidiodomycosis
Mild or non CNS blastomycosis
Chromoblastomycosis
Penicillium mameffei
(69)Prednisolone+itraconazole/Voriconazole
Allergic bronchopulmonary aspergillosis.
(70)Capsofungin
Candida glabarata,and candida krusei .

Drugs of choice in gastrointestinal disorders

(71)PPIs
Gastric ulcer ,Duodenal ulcer ,stress ulcer,NSAIDs-induced ulcer.
GERD,& Zolinger elison syndrome.
(72)Metoclopramide
Migraine associated or drug or disease associated vomiting
(73)Domperidone
Levodopa induced vomiting
(74)Ondansetron
Post operative or radiation induced vomiting
(75)5HT3 antagonist
Cisplatin induced early vomiting
(76)Lactulose
Hepatic encephalopathy
(77)Methyl naltrexone
Opioid induced constipation
(78)Octreotide
Diarhea in carcinoid syndrome

Drugs of choice in Hematological Disorders

(79)Warfarin
DVT prophylaxis
Chronic atrial fibrillation in mitral stenosis, advanced kidney disease and mechanical prosthetic heart valves
(80)Heparin+Warfarin
Initiation of therapy in DVT.
(81)Vitamin K
Warfarin overdose
(82)Protamine
Heparin overdose

Drugs of Choice in Hypertension

(83)Thiazide diuretics
Hypertension
(84)Prazosin
Hypertension With BPH
(85)Beta Blockers
Hypertension with ischemic heart disease.(Angina)
(86)ACE inhibitors
Hypertension with chronic kidney diseases.
(87)Alpha methylDopa
Hypertension in pregnancy
(88)Phentolamine
Hypertensive emergencies with cheese reaction
(89)Nitroprusside+Esmolol
Hypertensive emergencies in aortic dissection.
(90)Labetalol
Hypertensive emergencies in pregnancy .

Drugs of choice in shock

 (91)Adrenaline
Anaphylactic shock
(92)Dopamine or nor adrenaline
Cardiogenic shock
(93)Phenylephrine
Distributive shock
(94)Prazosin
Secondary shock
(95)Dopamine
Shock with oliguria
(96)Corticosteroids
Shock due to adrenal insufficiency

Drugs of choice For viral diseases

(97)Ribavirin
Viral hemorrhagic fever
Measles
Respiratory syncytial virus(in high-risk patient
(98)Zanamivir
Oseltamivir-resistant influenza
Oseltamivir
Seasonal influenza and avian influenza (bird flu)
(99)Acyclovir
Herpes simplex and varicella.
Valacyclovir
Acute herpes zoster.
(100)Gancyclovir
Cytomegalovirus retinitis.

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